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PUBLICATIONS

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  1. Ho N, Yap J, Zhao Z, Wang Y, Fernando K, Li CH, Kwang XL, Quah HS, Arcinas C, Iyer NG, Fong ELS, Bioengineered hydrogels recapitulate fibroblast heterogeneity in cancer, Advanced Science https://doi.org/10.1002/advs.202307129, March 2024

  2. Adine C, Fernando K, Ho N, Quah HS, Ho S, Wu KZR, Teng K, Arcinas C, Ha K, Li L, Chew J, Wang CH, Too N, Yeong JPS, Tan DSW, Tan IBH, Nagadia R, Chia C, Macalinao D, Bhuvaneswari H, Iyer NG, Fong ELS, Bioengineered hydrogels enhance ex vivo preservation of patient-derived tumor explants for drug testing, Biomaterials, March 2024

  3. Hu HQ, Krishaa L, Fong ELS, Magnetic force-based cell manipulation for in vitro tissue engineering, APL Bioeng., 2023, 7, 031504

  4. Wu KZ, Adine C, Mitriashkin A, Aw BJJ, Iyer NG, Fong ELS,  Making In Vitro Tumor Models Whole Again, Advanced Healthcare Materials, 2023 Jan 31;e2202279. doi: 10.1002/adhm.202202279.

  5. Lim TCJ, Kwang LG, Ho N, Toh C, Too N, Hooi L, Benoukraf T, Chow KHP, Dan YY, Chow KHE, Toh TB, Fong EL, Hepatocellular Carcinoma Organoid Co-Cultures Mimic Angiocrine Crosstalk to Generate Inflammatory Tumor Microenvironment, Biomaterials, 2022, Volume 284, 121527

  6. Foo MA, You M, Chan SL, Sethi G, Bonney GK, Yong WP, Chow EKH, Fong EL, Wang L, Goh BC, Clinical translation of patient-derived tumour organoids- bottlenecks and strategies, Biomarker Research, 2022 Mar 10;10(1):10

  7. Fong ELS, Iyer NG, Next generation in vitro tumor models guiding cancer therapy, Advanced Drug Delivery Reviews, 2021 Dec;179:114047

  8. Tang JWL, Zaseela A, Toh C, Adine A, Aydar AO, Iyer NG, Fong EL, Engineering Stromal Heterogeneity in Cancer. Advanced Drug Delivery Reviews. 2021 Aug;175:113817

  9. Too N, Ho N, Adine C, Iyer NG, Fong EL, Hot or cold: Bioengineering immune contextures into patient-derived in vitro tumor models. Advanced Drug Delivery Reviews. 2021 Aug;175:113791

  10. Luo XB, Fong EL*, Zhu C, Lin Q, Xiong M, Li A, Li T, Benoukraf T, Yu H, Liu S, Hydrogel-based colorectal cancer organoid co-culture models. Acta Biomaterialia. 2020. Dec 31;S1742-7061(20)30751-0.*co-first and corresponding author

  11. Fernando K, Kwang LG, Lim J, Fong EL, Hydrogels to Engineer Tumor Microenvironments In Vitro, Biomaterials Science. 2021, DOI: 10.1039/D0BM01943G

  12. Fong EL, Toh TB, Yu H, 3D cellulosic sponge for hepatocellular carcinoma patient-derived xenograft culture. SLAS Technology. 2021

  13. Sun M, Wong JY, Nugraha B, Ananthanarayanan A, Liu Z, Lee F, Gupta K, Fong ELS, Huang X, Yu H,            Cellulosic sponge for functional hepatic cell culture and retrieval. Biomaterials. 2019 

  14. Liu Z, Tasnim F, Huang XZ, Fong EL*, Yu H, Cost-effective robust synthesis of methacrylic cellulosic              sponge for spheroid culture. Cellulose. 2019 *corresponding author

  15. Yu Y, Wang J, Ng CW, Ma Y, Mo S, Fong ELS, Xing J, Song Z, Xie Y, Si K, Wee A, Welsch RE, So PTC, Yu H, Deep learning enables automated scoring of liver fibrosis stages. Sci Rep. 2018 Oct 30;8(1):16016.

  16. Zhu CJ, Luo XB, Fong EL, Wang Z, Bai Y, Han ZL, Liu S, Successful closure of esophagomediastinal fistula with endoclips and an endoloop after endoscopic submucosal dissection, Endoscopy. 2018 Apr; 50(4):E92-E94. doi:10.1055/s-0043-124181.

  17. Fong EL, Toh TB, Lin X, Liu Z, Nurrul Abdullah L, Mohd Abdul Rashid Masturah Bte, Benoukraf T, Chow E, Huynh H, Yu H, Datasets describing the growth and molecular features of hepatocellular carcinoma patient-derived xenograft cells grown in a three-dimensional macroporous hydrogel, Data in Brief. 2018 June;18: 594-606

  18. Fong EL*, Toh TB, Lin X, Liu Z, Nurrul Abdullah L, Mohd Abdul Rashid Masturah Bte, Benoukraf T, Chow    E, Huynh H, Yu H, Generation of Matched Patient-Derived Xenograft In Vitro-In Vivo Models using 3D Macroporous Hydrogels for the Study of Liver Cancer, Biomaterials. 2018 Mar;159:229-240.*corresponding author

  19. Yu Y, Wang J, Xu Y, Ha EC, Fong EL, Wee A, Yu H, Implementation of machine learning-aided imaging analytics for histopathological image diagnosis, Systems Medicine: Integrative, Qualitative and Computational Approaches

  20. Fong EL, Yu H, Organs-on-chips: Filtration enabled by differentiation, Nature Biomedical Engineering.      doi:10.1038/s41551-017-0074

  21. Fong EL, Toh TB, Yu H, Chow EKH, 3D Culture as a Clinically Relevant Model for Personalized Medicine, SLAS Technology. 2017 Jun; 22(3):245-253

  22. Gupta K, Song Z, Tang H, Fong EL, Ng IC, Yu H, Liver Tissue Engineering, Comprehensive Biomaterials  (Second Edition). 2017 Vol. 6, Pages 491-512

  23. Jie Y, Yang Y, Jeon WK, Tam ZY, Xu SY, Fong EL, Song Z, Tucker-Kellogg L, So P, Yu H, Development of a    Classification Model for Non-Alcoholic Steatohepatitis (NASH) using Confocal Raman Micro-Spectroscopy,  Journal of Biophotonics. 2017

  24. Li Q, Gupta K, Fan J, Fong EL, Song Z, Tang H, Ng IC, Ng CW, Kanchanawong P, Low BC, Vaisnoff V, Yu H, Actomyosin Contractility Drives Bile Regurgitation as an Early Homeostatic Response in  Obstructive Cholestasis, Journal of Hepatology. 2017 Jun;66(6):1231-1240.

  25. Chiu YC, Fong EL*, Grindel BJ, Kasper FK, Harrington DA, Farach-Carson MC, Sustained delivery of recombinant human bone morphogenetic protein-2 from perlecan domain I - functionalized electrospun poly (ε-caprolactone) scaffolds for bone regeneration. J Exp Orthop. 2016 Dec;3(1):25.  *co-first author

  26. Fong EL*, Harrington DA, Farach-Carson MC, Yu H, Heralding a New Paradigm in 3D Tumor Modeling,      Biomaterials. 2016 Sep 2;108:197-213. *corresponding author

  27. Liang Z, Xia H, Wang Z, Fong EL, Fan J, Seah YP, Zhang W, Li Q, Yu H, Vertical-flow Bioreactor Array Compacts Hepatocytes for Enhanced Polarity and Functions, Lab on a Chip. 2016, 16, 3898 - 3908

  28. Lam J, Clark EC, Fong EL, Lee EJ, Lu S, Tabata Y, Mikos AG, Data describing the swelling behavior and cytocompatibility of biodegradable polyelectrolyte hydrogels incorporating poly(L-lysine) for applications  in cartilage tissue engineering, Data in Brief. 2016 Mar 4;7:614-9

  29. Lam J, Clark EC, Fong EL, Lee EJ, Lu S, Tabata Y, Mikos AG, Evaluation of cell-laden polyelectrolyte hydrogels incorporating poly(L-lysine) for applications in cartilage tissue engineering, Biomaterials. 2016 Mar; 83:332-46

  30. Tong WH, Fang Y, Yan J, Hong X, Hari Singh N, Wang SR, Nugraha B, Xia L, Fong EL, Iliescu C, Yu H, Constrained spheroids for prolonged hepatocyte culture, Biomaterials. 2016 Feb; 80:106-20

  31. Fong EL, Wan XH, Yang J, Morgado M, Mikos AG, Harrington DA, Navone NM, Farach-Carson MC, A 3D in vitro model of patient-derived prostate cancer xenograft for controlled interrogation of in vivo tumor- stromal interactions, Biomaterials. 2016 Jan; 77:164-172

  32. Pan T, Fong EL, Martinez M, Harrington DA, Lin S-H, Farach-Carson MC, Satcher R, Three-dimensional (3D) culture of bone-derived human 786-O renal cell carcinoma retains relevant clinical characteristics of    bone metastases, Cancer Letters. 2015 Aug 28; 365(1):89-95

  33. Fong EL, Santoro M, Farach-Carson MC, Kasper FK, Mikos AG, Tissue Engineering Perfusable Cancer Models, Current Opinion in Chemical Engineering. 2014 Feb; 3:112-117

  34. Chang MA, Patel V, Gwede M, Morgado M, Tomasevich K, Fong EL, Farach-Carson MC, Delk NA, IL-1β induces p62/SQSTM1 and represses androgen receptor expression in prostate cancer cells, Journal of Cellular Biochemistry. 2014 Dec;115(12):2188-97

  35. Fong EL, Martinez M, Yang J, Mikos AG, Kasper FK, Harrington DA, Farach-Carson MC, Hydrogel-based    3D model of patient-derived prostate xenograft tumors suitable for drug screening. Molecular Pharmaceutics. 2014 Apr; 11(7):2040-2050

  36. Zarembinski TI, Engel BJ, Doty NJ, Constantinou PE, Onorato MV, Erickson IE, Fong EL, Martinez M, Milton RL, Danysh BP, Delk NA, Harrington DA, Farach-Carson MC, Carson DD, HyStem®, a Customizable  Hyaluronan-Based Hydrogel Matrix for 3D Cell Culture.  3D Cell Culture: Technology and Application. 2014

  37. Fong EL, Lamhamedi-Cherradi SE, Burdett E, Ramamoorthy V, Lazar AJ, Kasper FK, Farach-Carson MC,      Vishwamitra D, Demicco EG, Menegaz BA, Amin HM, Mikos AG, Ludwig JA, Modeling Ewing Sarcoma Tumors in vitro with 3D scaffolds, Proc Natl Acad Sci (PNAS) USA. 2013 Apr; 110(16):6500-5.

  38. Fong EL, Brendan M. Watson, F. Kurtis Kasper, Antonios G. Mikos, Building Bridges: Leveraging                  Interdisciplinary Collaborations in the Development of Biomaterials to Meet Clinical Needs. Advanced Materials. 2012 Sep; 24(36):4995-5013

  39. ​Fong EL, Chan CK, Goodman SB. Stem Cell Homing in Musculoskeletal Injury. Biomaterials. 2011 Jan;  32(2):395-409

  40. Chatterjee DK, Fong EL, Zhang Y. Nanoparticles in Photodynamic Therapy: An Emerging Paradigm,            Advanced Drug Delivery Reviews. 2008 Dec; 60(15):1627-37​​

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